Research

Working at the interface of engineering and biology, the LI Lab pursues innovative design and precision manufacturing to create biointegrated materials and devices that enable precise recording, understanding, and modulation of biological systems. We are particularly interested in applying these technologies to interrogate the complex nervous circuits, to identify and screen new biomarkers, and to manipulate microbial activities.

We envision that such biointegrated technologies will reshape the connections between the synthetic and biological worlds, leading to new solutions for future healthcare. 

Work in our lab can be broadly divided into the following interconnected domains:

 
 

Biosensor & Bioelectronics

References:
A tissue-like neurochemical sensor for brain and gut. Nature 606, 94-101, 2022.
Soft sensor tracks the neurochemical messengers dopamine and serotonin. Nature Research Briefing 2022.
Morphing electronics enable neuromodulation in growing tissue. Nature Biotechnology 2020.

Supported by NSF, Spartan Innovations.